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簡(jiǎn)要描述:Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor k
產(chǎn)品型號(hào):bsm-61185R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-03-02
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