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簡(jiǎn)要描述:CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal featu
產(chǎn)品型號(hào):bs-7907R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-26
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